Animal pain, perception and alleviation

Pain alleviation by vibratory stimulation.

In the present study 366 patients suffering acute or chronic musculoskeletal pain of different origin were given vibratory stimulation for the pain. Many of the patients had previously had treatments of various kinds without satisfactory relief. The effect of vibratory stimulation was assessed during and after stimulation using a graphic rating scale. Sixty-nine per cent of the patients reporte...

Recognition and Alleviation of Pain in Animals

Pain perception in neurodevelopmental animal models of schizophrenia.

Animal models are important for the investigation of mechanisms and therapeutic approaches in various human diseases, including schizophrenia. Recently, two neurodevelopmental rat models of this psychosis were developed based upon the use of subunit selective N-methyl-D-aspartate receptor agonists--quinolinic acid (QUIN) and N-acetyl-aspartyl-glutamate (NAAG). The aim of this study was to evalu...

Alleviation of pain associated with immunization injections.

Typically any new vaccine (or for that matter any new drug) has to undergo phase 1 (early safety and dosing study), phase 2 (safety, dosing and immunogenicity study) and phase 3 (field efficacy and further safety study) trials before being licensed(2). In case one brand of the concerned vaccine with satisfactory efficacy data is already licensed, and serological correlates of protection for the...

Promoting children’s pain alleviation in emergency department

Background Pain is, by nature, a subjective experience influenced by social, psychological, and experiential factors. Nowadays, pain relief is considered an imperative of the pediatric emergency nursing. Analgesia administration influences the entire child’s medical experience and can have a lasting effect on patient and family’s reaction to current and future medical cares [1]. Pain assessment...